Overview

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4 (Tβ4), a naturally occurring protein found in many tissues. It has attracted scientific interest due to its involvement in cellular migration, cytoskeletal organization, and tissue repair signaling pathways.

This product contains 5 mg of lyophilized TB-500 peptide, intended strictly for laboratory research purposes. It is not approved for human or veterinary use and is not intended for therapeutic applications.

Product Specifications

• Product Name: TB-500
• Quantity: 5 mg per vial
• Form: Lyophilized powder
• Purity: ≥98% (HPLC tested)
• Molecular Formula: C212H350N56O78S
• Sequence: Synthetic fragment of Thymosin Beta-4
• Intended Use: Research and laboratory applications only

What Is TB-500?

TB-500 is a synthetic peptide modeled after the active region of Thymosin Beta-4, a protein involved in actin binding and cellular structural regulation. In laboratory research, TB-500 is studied for its role in:

• Cell migration processes
• Cytoskeletal remodeling
• Tissue regeneration signaling
• Angiogenesis-related pathways

It is important to emphasize that these investigations are conducted in controlled research settings and do not represent approved medical uses.

Mechanism of Interest in Research

In scientific literature, Thymosin Beta-4–related peptides are studied for their influence on:

• Actin polymerization and depolymerization
• Cellular motility
• Wound-healing pathway modeling
• Inflammatory response modulation
• Vascular development signaling

Researchers explore how peptide fragments such as TB-500 interact with intracellular signaling mechanisms in vitro and in preclinical models.

Lyophilized Format & Stability

TB-500 is supplied as a lyophilized (freeze-dried) powder, which improves stability during transport and storage.

Storage Recommendations:

• Store at 2–8°C for short-term use
• Store at –20°C for long-term preservation
• Protect from moisture and repeated freeze-thaw cycles
• Keep away from direct light

Improper storage may compromise peptide integrity and experimental consistency.

Research Applications

TB-500 may be referenced in laboratory environments for studies involving:

• Cell culture assays
• Connective tissue research
• Molecular biology experiments
• Regenerative signaling pathway modeling
• Actin-binding protein research

All use must comply with institutional research guidelines and applicable regulations.

Quality Control & Testing

Each research-grade batch typically undergoes:

• High-Performance Liquid Chromatography (HPLC) purity testing
• Mass spectrometry analysis
• Batch documentation and labeling verification

Researchers should review the Certificate of Analysis (COA) for detailed batch-specific purity data.

Regulatory & Safety Notice

• Not approved by FDA, EMA, or other regulatory authorities for medical use
• Not intended for human consumption
• Not a dietary supplement
• Not for veterinary applications
• For laboratory research use only

Handling should be performed by qualified laboratory professionals using appropriate safety protocols and personal protective equipment (PPE).

Frequently Asked Questions (FAQ)

What is TB-500 used for?

TB-500 is used strictly in laboratory research involving cellular migration, cytoskeletal studies, and tissue regeneration signaling pathways. It is not approved for medical treatment.

Is TB-500 approved for human use?

No. TB-500 is not approved for therapeutic or clinical use by regulatory agencies.

What does “research use only” mean?

“Research use only” indicates that the product is intended exclusively for laboratory experimentation and not for human or animal consumption.

How should TB-500 be stored?

Short-term storage at 2–8°C is recommended. For long-term stability, store at –20°C and avoid repeated freeze-thaw cycles.

Is TB-500 a supplement?

No. TB-500 is not a dietary supplement and is not intended for ingestion.

What purity level is typical?

Research-grade TB-500 is commonly supplied with ≥98% purity verified through HPLC testing. Always consult the COA for confirmation.

Does TB-500 require special handling?

Yes. It should be handled by trained laboratory personnel under appropriate safety procedures.

Sample Neutral Research Feedback

Academic Laboratory:
“Batch purity was consistent with documentation. Suitable for in vitro experimental protocols.”

Independent Research Facility:
“Lyophilized material maintained structural integrity under recommended storage conditions.”

Biochemistry Technician:
“Documentation and labeling were clear and aligned with laboratory-grade material standards.”